| Identification | Back Directory | [Name]
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE | [CAS]
69304-16-1 | [Synonyms]
R-AMC, 2HCL
H-ARG-AMC HCL
H-ARG-AMC 2 HCL
ARGININE-AMC 2 HCL
CATHEPSIN H SUBSTRATE II, FLUOROGENIC
L-Arginine7-amido-4-methylcoumarinHCl
L-ARGININE 7-AMIDO-4-METHYLCOUMARIN DIHYDROCHLORIDE | [Molecular Formula]
C16H23Cl2N5O3 | [MDL Number]
MFCD00155578 | [MOL File]
69304-16-1.mol | [Molecular Weight]
404.29 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
acetic acid: water (1:1): 50mg/mL, clear, colorless to light yellow | [form ]
powder | [color ]
White to off-white | [InChI]
1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1 | [InChIKey]
PFLMUQNBZRXRHD-YDALLXLXSA-N | [SMILES]
Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)CCCNC(N)=N)ccc12 |
| Hazard Information | Back Directory | [Uses]
L-Arginine 7-Amido-4-methylcoumarin Dihydrochloride is a fluorogenic peptide-based substrate used in the monitoring of thrombin activity. | [Uses]
L-Arginine-7-amido-4-methylcoumarin hydrochloride has been used as a?substrate for cathepsin H from rat muscle homogenate and sarcoplasmic extract. It has also been used as a?substrate for arginine amino-peptidase from Daphnia homogenates and recombinant aminopeptidase?from Toxoplasma gondii. | [Biochem/physiol Actions]
L-Arginine-7-amido-4-methylcoumarin hydrochloride is a protease substrate. It is a specific substrate for cathepsin H and not for cathepsin L and B. |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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Merck KGaA
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www.sigmaaldrich.cn |
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