| Chemical Properties | Back Directory | [Melting point ]
188-190 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
573.1±45.0 °C(Predicted) | [density ]
1.417±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform: 30 mg/ml | [form ]
A crystalline solid | [pka]
6.53±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome.1 In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM. | [Uses]
LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM. | [storage]
Store at -20°C | [References]
1. Dhara, K., Lohar, S., Patra, A., et al. A new lysosome-targetable turn-on fluorogenic probe for carbon monoxide imaging in living cells Anal. Chem. 90(4),2933-2938(2018). |
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| Company Name: |
TargetMol
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| Tel: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
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