| Identification | Back Directory | [Name]
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE | [CAS]
6948-34-1 | [Synonyms]
Einecs 230-114-8
6-METHYLTHIOCHROMANONE
6-METHYLTHIOCHROMAN-4-ONE
6-methyl-4H-thiochromen-4-one
6-METHYLBENZOTHIOPRAN-4(4H)-ONE
6-METHYLBENZOTHIOPYRAN-4(4H)-ONE
6-methyl-2,3-dihydrothiochromen-4-one
2,3-dihydro-6-methyl-4H-1-benzothiopyran-4-one
3,4-Dihydro-6-methyl-2H-1-benzothiopyran-4-one | [EINECS(EC#)]
230-114-8 | [Molecular Formula]
C10H10OS | [MDL Number]
MFCD00089270 | [MOL File]
6948-34-1.mol | [Molecular Weight]
178.25 |
| Chemical Properties | Back Directory | [Melting point ]
41-45 °C(lit.) | [Boiling point ]
174 °C(Press: 10 Torr) | [density ]
1.200±0.06 g/cm3(Predicted) | [Fp ]
110 °C | [storage temp. ]
Sealed in dry,Room Temperature | [Appearance]
Light yellow to orange Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 6-methylthiobenzodihydropyran-4-one from 3-[(4-methylphenyl)thio]propionic acid: 20 g (0.1 mol) of 3-[(4-methylphenyl)thio]propionic acid was dissolved in a 1000 ml beaker containing 70 ml of concentrated sulphuric acid, and the reaction was carried out for 12 h at room temperature. Upon completion of the reaction, the reaction mixture was cooled in an ice-water bath to precipitate a large amount of yellow solid precipitate, which was subsequently filtered. The filter cake was washed sequentially with 5% sodium bicarbonate solution and distilled water until neutral. The crude product was purified by recrystallization from 50% ethanol solution to give 16.88 g of light yellow solid 6-methylthiobenzodihydropyran-4-one in 93% yield. | [References]
[1] Letters in Organic Chemistry, 2016, vol. 13, # 3, p. 206 - 216
[2] Journal of Chemical Research, 2004, # 6, p. 394 - 395
[3] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 13, p. 4569 - 4574
[4] Chinese Journal of Chemistry, 2011, vol. 29, # 4, p. 757 - 764
[5] Chemische Berichte, 1923, vol. 56, p. 1275 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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