| Identification | Back Directory | [Name]
N,N-DIMETHYL-4-(5-METHYL-1H-BENZO[D]IMIDAZOL-2-YL)BENZENAMINE | [CAS]
69570-95-2 | [Synonyms]
V-161
2-[4(-DiMethylaMino)phenyl]-5-MethylbenziMidazole, 95%
N,N-dimethyl-4-(6-methyl-1H-benzo[d]imidazol-2-yl)aniline
N,N-Dimethyl-4-(5-methyl-1H-benzimidazol-2-yl)-benzenamine
Dimethyl-[4-(5-methyl-1H-benzoimidazol-2-yl)-phenyl]-amine
Benzenamine, N,N-dimethyl-4-(6-methyl-1H-benzimidazol-2-yl)-
N,N-DIMETHYL-4-(5-METHYL-1H-BENZO[D]IMIDAZOL-2-YL)BENZENAMINE | [Molecular Formula]
C16H17N3 | [MDL Number]
MFCD11040716 | [MOL File]
69570-95-2.mol | [Molecular Weight]
251.33 |
| Chemical Properties | Back Directory | [Melting point ]
209.5-211.0 °C | [Boiling point ]
459.3±47.0 °C(Predicted) | [density ]
1.170±0.06 g/cm3(Predicted) | [pka]
11.85±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
V-161 is the orally active inhibitor for Na+-V-ATPase with an IC50 of 144 nM. V-161 inhibits Enterococcus hirae and Vancomycin-resistant Enterococcus faecium (VRE) under alkaline condition with MIC of 4 μg/mL and 4 μg/mL. V-161 inhibits colonization of VRE in mouse small intestine[1]. | [References]
[1] Suzuki K, et al., Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure. Nat Struct Mol Biol. 2024 Nov 21. DOI:10.1038/s41594-024-01419-y |
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