| Identification | Back Directory | [Name]
PHE-LEU-GLU-GLU-LEU | [CAS]
69729-06-2 | [Synonyms]
FLEEL
PHE-LEU-GLU-GLU-LEU
H-PHE-LEU-GLU-GLU-LEU-OH
phenylalanine-leucine-glutamine-glutamine-leucine
L-Leucine, L-phenylalanyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-
L-phenylalanyl-L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-leucine | [Molecular Formula]
C31H47N5O10 | [MDL Number]
MFCD00076877 | [MOL File]
69729-06-2.mol | [Molecular Weight]
649.73 |
| Chemical Properties | Back Directory | [Boiling point ]
1059.8±65.0 °C(Predicted) | [density ]
1.259±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [pka]
3.34±0.10(Predicted) | [Sequence]
Phe-Leu-Glu-Glu-Leu |
| Hazard Information | Back Directory | [Uses]
H-Phe-Leu-Glu-Glu-Leu-OH is a synthetic pentapeptide, which can be used as the substrate of vitamin K dependent carboxylase, and a glutamyl residue in the generated product is carboxylated[1][2]. | [References]
[1] Rich DH, et al. Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase. J Med Chem. 1981 Jun;24(6):706-11. DOI:10.1021/jm00138a013
[2] Rich DH, et al. Synthesis and biological properties of new hexapeptide substrates for vitamin K dependent carboxylase. Evidence for X-Pro cis/trans amide bond interconversions in prothrombin precursor fragment 18-23. J Med Chem. 1983 Jun;26(6):910-6. DOI:10.1021/jm00360a023 |
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