| Identification | Back Directory | [Name]
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- | [CAS]
6980-25-2 | [Synonyms]
3',4',5-Trihydroxy-7-methoxy-6-β-D-glucopyranosylflavone
3',4',5-Trihydroxy-7-methoxy-6-(β-D-glucopyranosyl)flavone
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-6-b-D-glucopyranosyl-5-hydroxy-7-methoxy-
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-β-D-glucopyranosyl-5-hydroxy-7-methoxy-
2-(3,4-Dihydroxyphenyl)-6-(β-D-glucopyranosyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- | [Molecular Formula]
C22H22O11 | [MDL Number]
MFCD00210559 | [MOL File]
6980-25-2.mol | [Molecular Weight]
462.4 |
| Chemical Properties | Back Directory | [Melting point ]
270℃ (acetic acid ) | [Boiling point ]
761.3±60.0 °C(Predicted) | [density ]
1.649±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
5.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1]. | [Definition]
ChEBI: A flavone C-glycoside that is isoorientin in which the hydroxy group at position 7 is replaced by a methoxy group. | [storage]
Store at -20°C | [References]
[1] Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541. DOI:10.18632/oncotarget.20913 |
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