| Identification | Back Directory | [Name]
(2S,3R,4E)-2-Amino-4-hexadecene-1,3-diol | [CAS]
6982-09-8 | [Synonyms]
16:Sphingosine
C16-Sphingosine
Hexadecasphingenine
Sphingosine (d16:1)
Hexadecasphing-4-enine
(2S,3R,E)-2-Amino-4-hexadecene-1,3-diol
(E,2S,3R)-2-aminohexadec-4-ene-1,3-diol
(2S,3R,4E)-2-Amino-4-hexadecene-1,3-diol
4-Hexadecene-1,3-diol, 2-amino-, (2S,3R,4E)- | [Molecular Formula]
C16H33NO2 | [MDL Number]
MFCD08703028 | [MOL File]
6982-09-8.mol | [Molecular Weight]
271.44 |
| Chemical Properties | Back Directory | [Boiling point ]
419.6±45.0 °C(Predicted) | [density ]
0.950±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible | [form ]
A crystalline solid | [pka]
11.80±0.45(Predicted) |
| Hazard Information | Back Directory | [Uses]
C16-Sphingosine has shown cytotoxicity towards human colon cancer cells. | [Definition]
ChEBI: Hexadecasphing-4-enine is a sphingoid that is the C16 analogue of sphingosine. It has a role as a mouse metabolite. It is a sphingoid and an aminodiol. It is a conjugate base of a hexadecasphing-4-enine(1+). | [Biological Activity]
Sphingosine is implicated in negative regulation of cell proliferation and stimulation of apoptosis. It has a potential to control the activities of phospholipasesprotein kinasesion channelscannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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