| Chemical Properties | Back Directory | [Melting point ]
187 °C (exothermic decomp onset @144.5 C)(lit.) | [storage temp. ]
2-8°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 25 mg/ml; Ethanol: 0.5 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5’-adenosyl)-L-methionine (SAM; Item No. 13956) can be converted to 5’-chloro-5’-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase.1 Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A (Item No. 10007311) in the marine bacterium S. tropica.1WARNING This product is not for human or veterinary use. |
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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