| Identification | Back Directory | [Name]
neoisoliquiritin | [CAS]
7014-39-3 | [Synonyms]
neoisoliquiritin
1-(2,4-Dihydroxyphenyl)-3-[4-(beta-D-glucopyranosyloxy)phenyl]-2-propen-1-one
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]- (9CI) | [Molecular Formula]
C21H22O9 | [MOL File]
7014-39-3.mol | [Molecular Weight]
418.4 |
| Hazard Information | Back Directory | [Chemical Properties]
It is soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from licorice. | [Uses]
neoisoliquiritin inhibits tumor progression by targeting GRP78-β-catenin signaling in human breast cancer cell xenograft mouse model. A cancer chemopreventive agent. | [Definition]
ChEBI: Isoliquiritin is a monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 2' and 4' and a beta-D-glucopyranosyloxy group at position 4 respectively. It has a role as an antineoplastic agent and a plant metabolite. It is a member of chalcones, a member of resorcinols, a beta-D-glucoside and a monosaccharide derivative. It is functionally related to a trans-chalcone. |
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