| Identification | Back Directory | [Name]
Pyrotinib Maleate | [CAS]
704881-43-6 | [Synonyms]
Nicousamide
Nicousamide Pyrotinib Maleate
Benzoic acid, 2-hydroxy-5-[[(7-hydroxy-8-methyl-6-nitro-2-oxo-2H-1-benzopyran-3-yl)carbonyl]amino]- | [Molecular Formula]
C18H12N2O9 | [MOL File]
704881-43-6.mol | [Molecular Weight]
400.3 |
| Hazard Information | Back Directory | [Uses]
Nicousamide is a potent inhibitor of TGF-β RII phosphorylation. Nicousamide can be used to study renal fibrosis in animal models of diabetic nephropathy[1]. | [References]
[1] Zhang H, et al. Nicousamide, a potent inhibitor of phosphorylation by TGF-β receptor II. Acta Pharmaceutica Sinica B, 2011, 1(3): 160-165. |
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