ChemicalBook--->CAS DataBase List--->70806-55-2

70806-55-2

70806-55-2 Structure

70806-55-2 Structure
IdentificationBack Directory
[Name]

trans-Tranilast
[CAS]

70806-55-2
[Synonyms]

trans-Tranilast
Tranilast (trans-)
trans-Tranilast, >98%
Tranilast Impurity 3 (trans-Tranilast)
2-(3,4-Dimethoxycinnamoylamino)benzoic acid
2-(3,4-Dimethoxy-trans-cinnamoylamino)benzoic acid
2-[[(2E)-3-(3,4-DiMethoxyphenyl)-1-oxo-2-propen-1-yl]aMino]benzoic Acid
Benzoic acid, 2-[[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
3-{2-[4-(6-FLUORO-1,2-BENZOXAZOL-3-YL)-1-PIPERIDINYL]ETHYL}-2-METHYL-7,8-DIHYDRO-4H-PYRIDO[1,2-A]PYRIMIDINE-4,9(6H)-DIONE
[Molecular Formula]

C18H17NO5
[MDL Number]

MFCD00864787
[MOL File]

70806-55-2.mol
[Molecular Weight]

327.33
Chemical PropertiesBack Directory
[Melting point ]

184 °C(Solv: water (7732-18-5); acetone (67-64-1))
[Boiling point ]

585.6±50.0 °C(Predicted)
[density ]

1.299±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO: 100 mg/mL (305.50 mM)
[form ]

Solid
[pka]

3.45±0.36(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

trans-Tranilast is used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
[Definition]

ChEBI: Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid.
Spectrum DetailBack Directory
[Spectrum Detail]

trans-Tranilast(70806-55-2)1HNMR
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