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70904-56-2

70904-56-2 Structure

70904-56-2 Structure
IdentificationBack Directory
[Name]

KYOTORPHIN
[CAS]

70904-56-2
[Synonyms]

YR
TYR-ARG
KYOTORPHIN
Tyr-Arg-OH
Kiotorphin
H-TYR-ARG-OH
L-Tyr-L-Arg-OH
kyotorphin acetate
KYOTORPHIN, BOVINE
L-Tyrosyl-L-arginine
L-Arginine, L-tyrosyl-
Nα-(L-Tyrosyl)-L-arginine
KYOTORPHIN ACETATE SALT, H-TYR-ARG-OH ACETATE SALT
(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-5-guanidinopentanoic acid
(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-guanidino-valeric acid
(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
(2S)-2-[[(2S)-2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]-5-[bis(azanyl)methylideneamino]pentanoic acid
[EINECS(EC#)]

-0
[Molecular Formula]

C15H23N5O4
[MDL Number]

MFCD00076700
[MOL File]

70904-56-2.mol
[Molecular Weight]

337.37
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

H2O: soluble20mg/mL, clear
[form ]

powder
[pka]

3.09±0.10(Predicted)
[color ]

white to beige
[Water Solubility ]

H2O: 20mg/mL, clear
[InChIKey]

KTMKVRFTDZZFFE-FXMYHANSSA-N
[SMILES]

NC(NCCC[C@@H](C(O)=O)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=N.C
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Definition]

ChEBI: Tyr-Arg is a dipeptide composed of L-tyrosine and L-arginine joined by a peptide linkage. It is a conjugate base of a L-tyrosiniumyl-L-arginine(1+).
[Biological Activity]

Kyotorphin is a neuroactive dipeptide (Tyr-Arg) shown to have analgesicneuroprotectiveand neuromodulatory properties. It is synthesized in nerve terminals and found in the brain and in cerebro-spinal fluid (CSF). Kyotorphin indirectly stimulates opioid receptors by releasing methionine enkephalin (met-enkephalin). CSF levels are lower in patients with persistent pain and in patients with Alzheimer′s disease.
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