| Identification | Back Directory | [Name]
GSK-3 Inhibitor IX, Control, MeBIO | [CAS]
710323-61-8 | [Synonyms]
GSK-3 Inhibitor IX, Control, MeBIO
GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem
2H-Indol-2-one, 6-bromo-3-[1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-1-methyl- | [Molecular Formula]
C17H12BrN3O2 | [MDL Number]
MFCD09037537 | [MOL File]
710323-61-8.mol | [Molecular Weight]
370.2 |
| Hazard Information | Back Directory | [General Description]
A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as an inactive control for Cdk1/cyclin B, Cdk5/p25, and GSK-3α/β (IC50 >92 μM for Cdk1/cyclin B, >100 μM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties. | [Biochem/physiol Actions]
Cell permeable: yes |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Merck Millipore
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1-400-889-1988 400-889-1988 |
| Website: |
http://www.merckmillipore.com |
| Company Name: |
Merck KGaA
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21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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