| Identification | Back Directory | [Name]
MELOXICAM SODIUM SALT HYDRATE | [CAS]
71125-39-8 | [Synonyms]
Meloxicam sodium salt
Mobec sodium salt hydrate
FRMZBLMVNUXMTO-UHFFFAOYSA-N
Metacam sodium salt hydrate
MELOXICAM SODIUM SALT HYDRATE
UH-AC 62XX sodium salt hydrate
Meloxicam hydrate sodium salt
4-hydroxy-2-methyl-n-(5-methyl-2-thiazolyl)-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate
Meloxicam sodium salt hydrate,4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate, Metacam sodium salt hydrate, Mobec sodium salt hydrate, UH-AC 6
Metacam hydrate sodium salt, Mobec hydrate sodium salt, UH-AC 62XX hydrate sodium salt, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide hydrate sodium | [Molecular Formula]
C14H12N3NaO4S2 | [MDL Number]
MFCD11046047 | [MOL File]
71125-39-8.mol |
| Hazard Information | Back Directory | [Uses]
Meloxicam sodium salt hydrate has been used:
- as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
- as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
- as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
- to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells
| [Biochem/physiol Actions]
Meloxicam, a member of the oxicam family, is a non-steroidal anti-inflammatory drug (NSAID). It is synthesized from piroxicam with aryl and the pyridyl ring substitution. Meloxicam is a cyclooxygenase-2 (COX-2) inhibitor, it may be useful in treating inflammation and pain. Meloxicam has been shown to stop thymulin-induced increas in concentration of cytokines and Nerve growth factor?(NGF) in the liver of rats. Meloxicam also suppresses tumor growth and may be capable of antagonizing cachexia?in vitro. It promotes apoptosis in hepatocellular carcinoma. |
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