| Identification | Back Directory | [Name]
Octenidine | [CAS]
71251-02-0 | [Synonyms]
NeoKodan
Win-41464
Octeniderm
Octenisept
OCTENIDINE
Win-41464-2
1,1'-Decamethylenebis(1,4-dihydro-4-(octylimino)pyridine)
1,1'-(1,10-Decanediyl)bis[1,4-dihydro-4-(octylimino)pyridine]
N，N’-[1，10-Decanediyldi-1(4H)-pyridinyl-4-ylidene]-bis(1-octanamine)
N,N'-(1,1'-(Decane-1,10-diyl)bis(pyridin-1(1H)-yl-4(1H)-ylidene))bis(octan-1-aMine) | [Molecular Formula]
C36H62N4 | [MDL Number]
MFCD00865987 | [MOL File]
71251-02-0.mol | [Molecular Weight]
550.9 |
| Chemical Properties | Back Directory | [Boiling point ]
609.3±55.0 °C(Predicted) | [density ]
0.94±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
14.60±0.70(Predicted) | [InChIKey]
ZVXNYZWXUADSRV-UHFFFAOYSA-N | [SMILES]
C(N1C=C/C(=N/CCCCCCCC)/C=C1)CCCCCCCCCN1C=C/C(=N/CCCCCCCC)/C=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
Octenidine Hydrochloride: C36H62N4?2HCl [70775-75-6]. Obtained as a solid from diethyl ether, melting point 215-217°C. | [Uses]
Anti-infective, topical. | [Definition]
ChEBI: Octenidine is a dihydropyridine. | [in vivo]
Octenidine reduces bacterial counts on mice wounds and inhibit meticillin-resistant Staphylococcus aureus (MRSA)[3]. | Animal Model: | Mice (a six-millimetre punch full-thickness wound was inoculated with MRSA suspension)[3] | | Dosage: | | | Administration: | Administrated once 24 hours post-wounding | | Result: | Accelerated healing and reduced by >3.6 log cfu/g bacterial counts on the wounds relative to the PBS-treated control.
Exhibited lower burden of the inflammatory cells, more mature collagen fibres and well-defined epithelialisation.
Inhibited the expression of MRSA and its biofilm genes by nearly 100%. |
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