| Identification | Back Directory | [Name]
(2,2-2H2)docosanoic acid | [CAS]
71607-34-6 | [Synonyms]
(2,2-2H2)Docosansure
(2,2-2H2)docosanoic acid
Docosanoic-2,2-d2acid (9CI)
Fettsuren, gesttigt, unverzweigt mit geradzahliger C-Kette und C-Zahl >= und einer endstndigen Carboxylgruppe11 | [EINECS(EC#)]
275-674-4 | [Molecular Formula]
C22H42D2O2 | [MOL File]
71607-34-6.mol | [Molecular Weight]
342.596 |
| Hazard Information | Back Directory | [Uses]
Docosanoic acid-d2 (Behenic acid-d2) is deuterium labeled Docosanoic acid (HY-W013049).
Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans[1][2][3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Moreira DK, et al. Evaluation of structured lipids with behenic acid in the prevention of obesity. Food Res Int. 2017 May;95:52-58. DOI:10.1016/j.foodres.2017.03.005
[3] Iijima H, et al. The inhibitory action of long-chain fatty acids on the DNA binding activity of p53. Lipids. 2006 Jun;41(6):521-7. DOI:10.1007/s11745-006-5000-2 |
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| Company Name: |
Enzo Biochem Inc
|
| Telephone: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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