| Identification | Back Directory | [Name]
6-DIAZO-5-OXO-D-NORLEUCINE | [CAS]
71629-86-2 | [Synonyms]
D-DON
H-D-Don-OH
H-6-DIAZO-5-OXO-D-NLE-OH
H-D-NLE(6-DIAZO-5-OXO)-OH
6-DIAZO-5-OXO-D-NORLEUCINE
H-6-DIAZO-5-OXO-D-NORLEUCINE
D-Norleucine,6-diazo-5-oxo- (9CI)
2-Amino-6-diazo-5-oxohexanolic
acid
6-DIAZO-5-OXO-D-2-AMINOHEXANOIC ACID
(R)-2-Amino-6-diazo-5-oxocaproic acid, (R)-6-Diazo-5-oxo-L-norleucine
D-DON, 6-Diazo-5-oxo-D-2-aMinohexanoic acid, H-D-Glu(diazoMethylketone)-OH | [Molecular Formula]
C6H9N3O3 | [MDL Number]
MFCD00063114 | [MOL File]
71629-86-2.mol | [Molecular Weight]
171.15 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [form ]
powder | [color ]
faint yellow to yellow-brown | [InChI]
1S/C6H10N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5,8H,1-2,7H2,(H,11,12) | [InChIKey]
OIMDBDVYUPKOAO-UHFFFAOYSA-N | [SMILES]
NC(CCC(=O)C=[N]=N)C(O)=O |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22 | [Safety Statements ]
36 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
6-Diazo-5-oxo-D-norleucine, a D-Glutamine (HY-100587) analog, is a γ-glutamyl transferase inhibitor[1]. | [Biological Activity]
6-Diazo-5-oxo-D-norleucine is the enantiomer of α amino acid 6-diazo-5-oxo-L-norleucine (DON). | [References]
[1] Inoue M, et al. Inactivation of renal gamma-glutamyl transferase by 6-diazo-5-oxo-L-norleucylglycine, an inactive precursor of affinity-labeling reagent. Proc Natl Acad Sci U S A. 1981 Jan;78(1):46-9. DOI:10.1073/pnas.78.1.46 |
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| Company Name: |
Nextpeptide Inc
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| Telephone: |
+86-0571-81612335 +8613336028439 |
| Website: |
http://www.nextpeptide.com/ |
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