| Identification | Back Directory | [Name]
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester | [CAS]
7163-25-9 | [Synonyms]
3-Hydroxy-2-naphthoic acid ethyl ester
Ethyl 3-hydroxynaphthalene-2-carboxylate
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester
2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester | [Molecular Formula]
C13H12O3 | [MDL Number]
MFCD00220608 | [MOL File]
7163-25-9.mol | [Molecular Weight]
216.24 |
| Chemical Properties | Back Directory | [Melting point ]
79.0 to 83.0 °C | [Boiling point ]
291°C(lit.) | [density ]
1.1652 (rough estimate) | [refractive index ]
1.5090 (estimate) | [pka]
9.53±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
To a round bottom flask were added 5 g 3-hydroxy-2-naphthalic acidand 16 mL ethanol. The reaction mixture was refluxed for 6 h. After thecompletion of the reaction, the reaction mixture was cooled down to room temperature and washed with distilled water. The organic layerwas recovered and washed with saturated sodium bicarbonate followedby drying with anhydrous MgSO4. The MgSO4 was removed by filtrationand the filtrate was dried under reduced pressure. The resulted solid waspurified by silica chromatography with petroleum ether and ethyl acetate(10:1, v/v) as eluent to give the compound ethyl 3-hydroxy-2-naphthoate(4.1229 g, yield 70.60%). |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Cochemical Ltd.
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| Telephone: |
029-86115547 17791676824 |
| Website: |
http://www.cochemical.com |
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