| Identification | Back Directory | [Name]
Benzoic acid, 2-chloro-5-[(cyclopropylamino)sulfonyl]- | [CAS]
716358-51-9 | [Synonyms]
h-NTPDase8-IN-1
2-Chloro-5-(N-cyclopropylsulfamoyl)benzoic Acid
Benzoic acid, 2-chloro-5-[(cyclopropylamino)sulfonyl]- | [Molecular Formula]
C10H10ClNO4S | [MOL File]
716358-51-9.mol | [Molecular Weight]
275.71 |
| Hazard Information | Back Directory | [Uses]
h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer[1]. | [References]
[1] Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for?h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915. DOI:10.1039/d3ra03874b |
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