| Identification | Back Directory | [Name]
9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID | [CAS]
71953-80-5 | [Synonyms]
TXB3
DELTA17-TXB2
THROMBOXANE B3
OYPPJMLKAYYWHH-NXJDUNGTSA-N
9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID
(5Z,13E,15S,17Z)-9α,11,15-Trihydroxythromboxa-5,13,17-trien-1-oic acid
7-[4,6-dihydroxy-2-(3-hydroxyocta-1,5-dienyl)oxan-3-yl]hept-5-enoic acid
(E)-7-[4,6-dihydroxy-2-[(1E,5E)-3-hydroxyocta-1,5-dienyl]oxan-3-yl]hept-5-enoic acid
(Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]oxan-3-yl]hept-5-enoic acid
(Z)-7-[(2R,3S,4S,6S)-4,6-dihydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]oxan-3-yl]hept-5-enoic acid | [Molecular Formula]
C20H32O6 | [MDL Number]
MFCD00216087 | [MOL File]
71953-80-5.mol | [Molecular Weight]
368.46 |
| Chemical Properties | Back Directory | [solubility ]
DMF: >50 mg/ml (from TXB2); DMSO: >25 mg/ml (from TXB2); Ethanol: >100 mg/ml (from TXB2); PBS pH 7.2: >100 μg/ml (from TXB2) |
| Hazard Information | Back Directory | [Description]
Thromboxane B3 (TXB3) is the stable hydrolysis product of TXA3 synthesized from eicosapentaenoic acid (EPA; ) by COX and thromboxane synthase. It is biosynthesized in various tissues such as seminal vesicles, lung, PMNL, and ocular tissues. | [Uses]
Thromboxane B3 (TXB3) is the stable hydrolysis product of TXA3 synthesized fromeicosapentaenoic acid (EPA; ) by COX and thromboxane synthase. It is biosynthesized in various tissues such as seminal vesicles, lung, PMNL, and ocular tissues.[Cayman Chemical] | [Definition]
ChEBI: A member of the class of thromboxanes B that is (5Z,13E,17Z)-thromboxa-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. | [References]
[1] P S KULKARNI B D S P L Kaufman. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid.[J]. Journal of ocular pharmacology, 1987, 3 4: 349-356. DOI: 10.1089/jop.1987.3.349
[2] PRASAD S. KULKARNI B. D S. Eicosapentaenoic acid metabolism in human and rabbit anterior uvea[J]. Prostaglandins, 1986, 31 6: Pages 1159-1164. DOI: 10.1016/0090-6980(86)90217-0 |
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