| Identification | Back Directory | [Name]
{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxy-4-oxobutyl]sulfanyl}methyl benzoate | [CAS]
720671-77-2 | [Synonyms]
AB131
{[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methoxy-4-oxobutyl]sulfanyl}methyl benzoate | [Molecular Formula]
C21H19NO6S | [MOL File]
720671-77-2.mol | [Molecular Weight]
413.444 |
| Hazard Information | Back Directory | [Uses]
AB131 is a MSMEG 6649 and Rv2172c inhibitor (Kd: 0.16 and 0.02 μM respectively). AB131 can sensitize the antimycobacterial activity of the antitubercular agent[1]. | [References]
[1] Li J, et al. Identification of a Potential Antimycobacterial Drug Sensitizer Targeting a Flavin-Independent Methylenetetrahydrofolate Reductase. ACS Omega. 2023 Oct 4;8(41):38406-38417. DOI:10.1021/acsomega.3c05021 |
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