| Identification | Back Directory | [Name]
L-Thyroxine-[L-Tyr-ring-13C6] hydrochloride | [CAS]
720710-30-5 | [Synonyms]
L-Thyroxine-13C6 solution
L-Tyr-ring-13C6]-Thyroxine Hydrochloride
Thyroxine-[L-Tyr-ring-13C6] hydrochloride
Thyroxine-[L-Tyr-ring-13C6] Hydrochloride (Solution)
L-Thyroxine-[L-Tyr-ring-13C6] hydrochloride (Solution)
L-Thyroxine-[L-Tyr-ring-13C6] hydrochloride (CertiMass solution)
L-Tyrosine-1,2,3,4,5,6-13C6, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo- | [EINECS(EC#)]
200-659-6 | [Molecular Formula]
C15H11I4NO4 | [MOL File]
720710-30-5.mol | [Molecular Weight]
782.83 |
| Chemical Properties | Back Directory | [density ]
2.636±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [Fp ]
9℃ | [storage temp. ]
-20°C | [form ]
liquid | [color ]
White to off-white | [Major Application]
clinical testing | [InChI]
1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1/i1+1,2+1,6+1,10+1,11+1,14+1 | [InChIKey]
XUIIKFGFIJCVMT-PDHVKVOFSA-N | [SMILES]
I[13C]1=[13C]([13C](I)=[13CH][13C](C[C@@H](C(O)=O)N)=[13CH]1)OC2=CC(I)=C(O)C(I)=C2 |
| Hazard Information | Back Directory | [Uses]
The Certified Reference Material (CRM) in solution can also be used as an internal standard as follows:- Combination of hollow fiber-liquid-phase microextraction (HF-LPME) based sample preparation and liquid chromatography-tandem mass spectrometric (LC-MS/MS) determination of total thyroxine in serum samples
- Development of an LC-MS/MS method for the multi-residue analysis of melatonin, cortisol, triiodothyronine, thyroxine, and testosterone in r at serum samples following their dual liquid-liquid extraction
- Simultaneous determination of thyroxine by an isotope dilution-matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) method from human serum samples
- Estimation of thyroxine (T4) and triiodothyronine (T3) in r at cardiac tissue samples by a high-performance liquid chromatographic-tandem mass spectrometric (HPLC-MS/MS) method following their derivatization
- Establishing and validating an LC-MS/MS-based method for the quantification of endogenous thyroid hormones, T4 and two of its T3 isomers, in tissue samples obtained from lamprey, following the enzymatic digestion and protein precipitation of the samples
| [General Description]
Thyroxine or T4 is a thyroid hormone responsible for regulation of protein, fat, and carbohydrate metabolism as well as the proper development and differentiation of all cells of the human body. This internal standard and Certified Spiking Solution? is suitable for quantitation of free and total T4 serum levels by LC-MS/MS for determination of hyper- or hypothyroidism and monitoring treatment with synthetic thyroid hormones. |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
|