| Identification | Back Directory | [Name]
Benzoic acid, 4-[3-[3-(3-hydroxyoctyl)-4-oxo-2-thiazolidinyl]propyl]- | [CAS]
72313-41-8 | [Synonyms]
698
L-644,698
Benzoic acid, 4-[3-[3-(3-hydroxyoctyl)-4-oxo-2-thiazolidinyl]propyl]- | [Molecular Formula]
C21H31NO4S | [MDL Number]
MFCD05662263 | [MOL File]
72313-41-8.mol | [Molecular Weight]
393.54 |
| Hazard Information | Back Directory | [Description]
L-644,698 is a novel selective human prostanoid DP receptor agonist. | [Uses]
L-644698 is a potent and selective human recombinant prostaglandin D2 (PGD2) receptor (hDP) agonist with Ki values of 0.9, 267, 3730, 9280 nM for hDP, hEP2, hEP3, hEP4, respectively. L-644698 induces cyclic AMP production with an EC50 value of 0.5 nM[1]. | [IC 50]
hDP receptor: 0.9 nM (Ki); hEP2: 267 nM (Ki); hEP3: 3730 nM (Ki); hEP4: 9280 nM (Ki) | [References]
[1] Wright DH, et al. Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. Br J Pharmacol. 1998 Apr;123(7):1317-24. DOI:10.1038/sj.bjp.0701708 |
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