| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, 2-chloro-N-[4′-(trimethylsilyl)[1,1′-biphenyl]-2-yl]- | [CAS]
723748-50-3 | [Synonyms]
3-Pyridinecarboxamide, 2-chloro-N-[4′-(trimethylsilyl)[1,1′-biphenyl]-2-yl]- | [Molecular Formula]
C21H21ClN2OSi | [MOL File]
723748-50-3.mol | [Molecular Weight]
380.94 |
| Hazard Information | Back Directory | [Uses]
SDH-IN-18 (Compound 3a) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 8.70 mg/L. SDH-IN-18 destroys fungal morphology and reproduction, exhibits antifungal activity against Rhizoctonia solani and Sclerotinia sclerotiorum with EC50 of 0.48 and 1.4 mg/L[1]. | [References]
[1] Quan X, et al., Design, Synthesis, and Biological Activity of Silicon-Containing Carboxamide Fungicides. J Agric Food Chem. 2024 Aug 7;72(31):17260-17270. DOI:10.1021/acs.jafc.4c03001 |
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