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724760-19-4

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724760-19-4 Structure

724760-19-4 Structure
IdentificationBack Directory
[Name]

RC-100
[CAS]

724760-19-4
[Synonyms]

RC-100
RETROCYCLIN-1
Retrocyclin-1 RC-100
CYCLO(-GLY-ILE-CYS-ARG-CYS-ILE-CYS-GLY-ARG-GLY-ILE-CYS-ARG-CYS-ILE-CYS-GLY-ARG)
CYCLO(-GLY-ILE-CYS-ARG-CYS-ILE-CYS-GLY-ARG-GLY-ILE-CYS-ARG-CYS-ILE-CYS-GLY-ARG), (DISULFIDE BONDS BETWEEN CYS3 AND CYS16/CYS5 AND CYS14/CYS7 AND CYS12)
[Molecular Formula]

C74H128N30O18S6
[MDL Number]

MFCD08458564
[MOL File]

724760-19-4.mol
[Molecular Weight]

1918.39
Chemical PropertiesBack Directory
[density ]

1.58±0.1 g/cm3(Predicted)
[pka]

12.43±0.70(Predicted)
[Sequence]

Phe-Leu-Gly-Gly-Leu-Ile-Lys-Ile-Val-Pro-Ala-Met-Ile-Cys-Ala-Val-Thr-Lys-Lys-Cys-OH(Disulfide bond)
Hazard InformationBack Directory
[Uses]

Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM)[1].
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