| Identification | Back Directory | [Name]
Pirarubicin | [CAS]
72496-41-4 | [Synonyms]
1609rb
THP-ADM
Pirabucin
Pinorubicin
THEPRUBICIN
PIRARUBICIN
Tepirubicin
Therarubiein
Therarubicin
THP-adriamycin
Pirarubicin(BICINS)
PIRARUBICIN HYDROCHLORIDE
Pirarubicin(THP-AdriaMycin)
(8s-cis)-droxyacetyl)-1-methoxy
4’-o-tetrahydropyranyladriamycin
4’-o-tetrahydropyranyldoxorubicin
5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y
l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy
(8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
(8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
(8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
(7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione | [Molecular Formula]
C32H37NO12 | [MDL Number]
MFCD00869742 | [MOL File]
72496-41-4.mol | [Molecular Weight]
627.64 |
| Chemical Properties | Back Directory | [Appearance]
Red Solid | [Melting point ]
188-192°C (dec.) | [alpha ]
D25 +175 ±25° (c = 0.2 in CHCl3) | [Boiling point ]
834.7±65.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
ethanol: soluble25mg/mL | [form ]
powder | [pka]
7.35±0.60(Predicted) | [color ]
Orange to Red | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Red Solid | [Usage]
Structural analog of Doxorubicin. Antineoplastic | [Description]
Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In
acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is
reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be
myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting. | [Originator]
Meiji Seika (Japan) | [Uses]
Structural analog of Doxorubicin. Antineoplastic | [Definition]
ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline. | [Brand name]
Pinorubicin; Therarubucin |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Telephone: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
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