| Identification | Back Directory | [Name]
4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE | [CAS]
7279-75-6 | [Synonyms]
Salmeterol-d
isoetarine mesilate
ISOETHARINE MESYLATE
ISOETHARINE MESYLATE SALT
SOYAGMVKMXZVNZ-UHFFFAOYSA-N
4-[1-HYDROXY-2-[(1-METHYLETHYL)AMINO]BUTYL]-1,2-BENZENEDIOL MESYLATE SALT
4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE
4-[1-hydroxy-2-(propan-2-ylamino)butyl]benzene-1,2-diol,methanesulfonic acid
Adrenergic Receptor,Beta Receptor,Inhibitor,Isoetarine,catechol-like,β-adrenergic Receptors Agonist,emphysema,Isoetharine mesylate salt,inhibit,COMT,bronchodilator,bronchitis,Isoetharine | [EINECS(EC#)]
230-695-8 | [Molecular Formula]
C14H25NO6S | [MDL Number]
MFCD00133422 | [MOL File]
7279-75-6.mol | [Molecular Weight]
335.42 |
| Hazard Information | Back Directory | [Uses]
chelating agent | [Uses]
Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. Also, it is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression. | [Brand name]
Bronk ometer (Sanofi Aventis). | [Biological Activity]
Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway. | [in vivo]
Isoetharine mesylate inhibits melanin deposition with the AC50 value of 5.10 mM and complete inhibition of pigment production at 7.50 mM in the zebrafish larvae model[2]. | [IC 50]
β adrenergic receptor |
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