| Chemical Properties | Back Directory | [Boiling point ]
845.8±65.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [pka]
8.08±0.70(Predicted) | [InChIKey]
YQVKSZNVVCIETH-NYSCBQEQNA-N |
| Hazard Information | Back Directory | [Description]
20-O-Demethyl-AP3 is a secondary metabolite derived from Ansamitocin P-3, and Ansamitocin P-3 is a macrocyclic antitumor antibiotic exerting its therapeutic effects by inhibiting microtubules.
| [Uses]
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic[1]. | [References]
[1] Zhongfa Liu, et al. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. J Mass Spectrom. 2005 Mar;40(3):389-99. DOI:10.1002/jms.800 |
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