ChemicalBook--->CAS DataBase List--->73090-70-7

73090-70-7

73090-70-7 Structure

73090-70-7 Structure
IdentificationBack Directory
[Name]

EPIROPRIM
[CAS]

73090-70-7
[Synonyms]

EPIROPRIM
Ro-11-8958
Epiroprime
Fenarimol Impurity 2 (Triarimol)
5-(3,5-DIETHOXY-4-PYRROL-1-YL-BENZYL)-PYRIMIDINE-2,4-DIAMINE
2,4-Diamino-5-[3,5-diethoxy-4-(1H-pyrrol-1-yl)benzyl]pyrimidine
EPIROPRIM:5-(3,5-DIETHOXY-4-PYRROL-1-YL-BENZYL)-PYRIMIDINE-2,4-DIAMINE
[Molecular Formula]

C19H23N5O2
[MDL Number]

MFCD00865113
[MOL File]

73090-70-7.mol
[Molecular Weight]

353.418
Chemical PropertiesBack Directory
[Boiling point ]

486.84°C (rough estimate)
[density ]

1.2174 (rough estimate)
[refractive index ]

1.7600 (estimate)
Hazard InformationBack Directory
[Uses]

Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor. Epiroprim displays excellent activity against staphylococci, enterococci, pneumococci, and streptococci[1].
[References]

[1] H H Locher, et al. Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone. Antimicrob Agents Chemother. 1996 Jun;40(6):1376-81. DOI:10.1128/AAC.40.6.1376
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2734-70-5

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