| Identification | Back Directory | [Name]
EPA | [CAS]
73167-03-0 | [Synonyms]
EPA
ICOSAPENT
C20:5 OMEGA-3
TIMNODONIC ACID
Icosapent sodium
EICOSAPENTAENOIC CID
EICOSAPENTAENOIC ACID
EPA 5C,8C,11C,14C,17C
ALL CIS 5-8-11-14-17 EPA
Eicosapentaenoic Acid (sodium)
C20:5 (ALL CIS-5,8,11,14,17) ACID
5,8,11,14,17-EICOSAPENTAENOIC ACID
Eicosapentaenoic Acid (sodium salt)
CIS-5,8,11,14,17-EICOSAPENTANEOIC ACID
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID
EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID
ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID
ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
5,8,11,14,17-eicosapentaenoic acid, sodium salt
cis-5,8,11,14,17-eicosapentaenoic acid*sodium app
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID SODIUM SALT
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*S ODIUM APPRO
(all-Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt
sodium:(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt
tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
5,8,11,14,17-Eicosapentaenoicacid, sodium salt (1:1), (5Z,8Z,11Z,14Z,17Z)- | [Molecular Formula]
C20H29O2.Na | [MDL Number]
MFCD00065716 | [MOL File]
73167-03-0.mol | [Molecular Weight]
324.44 |
| Chemical Properties | Back Directory | [Melting point ]
−54-−53 °C(lit.) | [density ]
0.943 g/mL at 25 °C(lit.) | [refractive index ]
n20/D 1.4977(lit.) | [storage temp. ]
-20°C | [solubility ]
Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml | [form ]
waxy solid | [color ]
white | [biological source]
synthetic (organic) |
| Hazard Information | Back Directory | [Uses]
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
- to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
- to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
- to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
| [Uses]
reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis. | [General Description]
Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil. | [Biochem/physiol Actions]
Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis. | [IC 50]
Human Endogenous Metabolite |
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Sigma-Aldrich
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