ChemicalBook--->CAS DataBase List--->73167-03-0

73167-03-0

73167-03-0 Structure

73167-03-0 Structure
IdentificationBack Directory
[Name]

EPA
[CAS]

73167-03-0
[Synonyms]

EPA
ICOSAPENT
C20:5 OMEGA-3
TIMNODONIC ACID
Icosapent sodium
EICOSAPENTAENOIC CID
EICOSAPENTAENOIC ACID
EPA 5C,8C,11C,14C,17C
ALL CIS 5-8-11-14-17 EPA
Eicosapentaenoic Acid (sodium)
C20:5 (ALL CIS-5,8,11,14,17) ACID
5,8,11,14,17-EICOSAPENTAENOIC ACID
Eicosapentaenoic Acid (sodium salt)
CIS-5,8,11,14,17-EICOSAPENTANEOIC ACID
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID
5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID
EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID
ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID
ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID
5,8,11,14,17-eicosapentaenoic acid, sodium salt
cis-5,8,11,14,17-eicosapentaenoic acid*sodium app
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID SODIUM SALT
CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*S ODIUM APPRO
(all-Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt
sodium:(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate
(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt
tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
5,8,11,14,17-Eicosapentaenoicacid, sodium salt (1:1), (5Z,8Z,11Z,14Z,17Z)-
[Molecular Formula]

C20H29O2.Na
[MDL Number]

MFCD00065716
[MOL File]

73167-03-0.mol
[Molecular Weight]

324.44
Chemical PropertiesBack Directory
[Melting point ]

−54-−53 °C(lit.)
[density ]

0.943 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.4977(lit.)
[storage temp. ]

-20°C
[form ]

waxy solid
[color ]

white
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

34
[Safety Statements ]

26-36/37/39-45
[RIDADR ]

UN 3265 8/PG 3
[WGK Germany ]

3
[F ]

8-10-23
Hazard InformationBack Directory
[Uses]

cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
  • to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
  • to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
  • to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
[Uses]

reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis.
[General Description]

Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.
[Biochem/physiol Actions]

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.
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