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7336-44-9

7336-44-9 Structure

7336-44-9 Structure
IdentificationBack Directory
[Name]

(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
[CAS]

7336-44-9
[Synonyms]

N-Methylcolchamine
N-Methyldemecolcine
(S)-7-(Dimethylamino)-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
[Molecular Formula]

C22H27NO5
[MOL File]

7336-44-9.mol
Chemical PropertiesBack Directory
[Melting point ]

206-8°C
Safety DataBack Directory
[HS Code ]

2922509090
[Toxicity]

LD50 intramuscular in mouse: 200mg/kg
Hazard InformationBack Directory
[Description]

A colchicine type alkaloid, N-methylcolchamine occurs in Merendera robusta Bge. It is laevorotatory having a specific rotation of [α]D - 109° (CHC13). The structure has been established from spectroscopic data and by comparison with colchamine.
[References]

Salen et at., Collect. Czech. Chem. Commun., 28, 3413 (1963)
Trudykulov, Yusupov, Sadykov, Khim. Prir. Soedin., (1972)
Yusupov, Tr. Tashkent Nauch. Uzbek SSR, 20, 24 (1972)
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