| Hazard Information | Back Directory | [Description]
AC-7954 is a novel potent and efficacious nonpeptidic urotensin II receptor agonist. | [Uses]
AC-7954 free base is a selective nonpeptidic urotensin receptor agonist (EC50: 300 nM at the human UII receptor)[1]. | [Definition]
ChEBI: 3-(4-chlorophenyl)-3-[2-(dimethylamino)ethyl]-3,4-dihydro-1H-2-benzopyran-1-one is a 2-benzopyran. | [References]
[1] Croston GE, et al. Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954). J Med Chem. 2002 Nov 7;45(23):4950-3. DOI:10.1021/jm025551+ |
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