| Identification | Back Directory | [Name]
28-deMethyl -β-aMyrone | [CAS]
73493-60-4 | [Synonyms]
Nor-beta-amyrone
28-Nor-β-amyrenone
28-Nor-beta-amyrenone
28-deMethyl -β-aMyrone
28-demethyl -β-amyrone
28-Demethyl-beta-amyrone
3-oxo-28-norolean-12-ene
28-Nor-beta-amyren-3-one | [Molecular Formula]
C29H46O | [MDL Number]
MFCD29917566 | [MOL File]
73493-60-4.mol | [Molecular Weight]
410.67 |
| Hazard Information | Back Directory | [Uses]
28-Demethyl-β-amyrone (28-Norolean-12-en-3-one) is one of the main triterpenes from Pistacia lentiscus var. Chia[1]. 28-Demethyl-β-amyrone is an antitoxin and can effectively for the toxic effects of Staphylococcal enterotoxins (SEs)[2]. | [Synthesis]
β-Carvacrol (100 mg, 1.0 eq) was dissolved in DCM (20.0 mL) and cooled to 0°C. To this was added PCC (76 mg, 1.5 eq) and the mixture was stirred at room temperature for 1 hour. The progress of the reaction was monitored on TLC (hexane: EA6:1). The reactio | [References]
[1] Assimopoulou AN, et al. GC-MS analysis of penta- and tetra-cyclic triterpenes from resins of Pistacia species. Part II. Pistacia terebinthus var. Chia. Biomed Chromatogr. 2005 Oct;19(8):586-605. DOI:10.1002/bmc.484
[2] Kurjogi M, et al. Computational Modeling of the Staphylococcal Enterotoxins and Their Interaction with NaturalAntitoxin Compounds. Int J Mol Sci. 2018 Jan 3;19(1). DOI:10.3390/ijms19010133 |
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