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73532-83-9

73532-83-9 Structure

73532-83-9 Structure
IdentificationBack Directory
[Name]

1-arabinofuranosylcytosine-5'-stearylphosphate
[CAS]

73532-83-9
[Synonyms]

YNK-01
Fosteabine
Stearyl-ara-CMP
Fosteabine (Cytarabine ocfosfate
Fosteabine (Synonyms: Cytarabine ocfosfate
1-arabinofuranosylcytosine-5'-stearylphosphate
2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-
4-Amino-1-[5-O-[(hydroxy)(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-1,2-dihydropyrimidin-2-one
[Molecular Formula]

C27H50N3O8P
[MDL Number]

MFCD31746875
[MOL File]

73532-83-9.mol
[Molecular Weight]

575.68
Chemical PropertiesBack Directory
[Boiling point ]

711.6±70.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

1.44±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

Fosteabine is an oral and proagent analogue of cytarabine which is resistant to deoxycytidine deaminase.
[Definition]

ChEBI: Cytarabine ocfosfate is a pyrimidine ribonucleoside monophosphate.
[References]

[1] Maloisel F, et al. Results of a phase II trial of a combination of oral cytarabine ocfosfate (YNK01) and interferon alpha-2b for the treatment of chronic myelogenous leukemia patients in chronic phase. Leukemia. 2002 Apr;16(4):573-80. DOI:10.1038/sj.leu.2402433
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