| Identification | Back Directory | [Name]
SIB-1893 | [CAS]
7370-21-0 | [Synonyms]
SIB 1893 >99%, solid
2-Methyl-6-styryl-pyridine
[e]-2-methyl-6-[2-phenylethenyl]pyridine
Pyridine, 2-methyl-6-[(1E)-2-phenylethenyl]- | [Molecular Formula]
C14H13N | [MDL Number]
MFCD02262120 | [MOL File]
7370-21-0.mol | [Molecular Weight]
195.26 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: 18 mg/mL | [form ]
solid | [InChI]
1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+ | [InChIKey]
SISOFUCTXZKSOQ-ZHACJKMWSA-N | [SMILES]
Cc1cccc(\C=C\c2ccccc2)n1 |
| Hazard Information | Back Directory | [Uses]
SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies. | [Definition]
ChEBI: 2-methyl-6-(2-phenylethenyl)pyridine is a member of styrenes. | [Biological Activity]
SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2''Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|