| Identification | Back Directory | [Name]
(ISOCYANOIMINO)TRIPHENYLPHOSPHORANE | [CAS]
73789-56-7 | [Synonyms]
Nsc371099
(N-Isocyanoi
N-isocyaniminotriphenylphosphorane
(ISOCYANOIMINO)TRIPHENYLPHOSPHORANE
(N-Isocyanoimino)Triphenylphosphorane
(Isocyanoimino)triphenylphosphorane>
(N-Isocyanoimino)triphenylphosphorane 95%
1-methylidyne-2-(triphenyl-lambda~5~-phosphanylidene)diazanium
1-methylidyne-2-(triphenyl-lambda~5~-phosphanylidene)diazani... | [Molecular Formula]
C19H15N2P | [MDL Number]
MFCD09038528 | [MOL File]
73789-56-7.mol | [Molecular Weight]
302.31 |
| Chemical Properties | Back Directory | [Melting point ]
160-161 °C | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
solid | [color ]
White to Light yellow to Light orange | [Major Application]
peptide synthesis | [InChI]
1S/C19H15N2P/c1-20-21-22(17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19/h2-16H | [InChIKey]
NIDTXBFHPXMXTR-UHFFFAOYSA-N | [SMILES]
[P](=N[N+]#[C-])(c3ccccc3)(c2ccccc2)c1ccccc1 |
| Hazard Information | Back Directory | [Uses]
Despite growing interest for therapeutic and other biological applications, cyclic peptidomimetics are challenging to synthesize. As reported by the lab of Andrei Yudin, (N-isocyanoimino)triphenylphosphorane (Pinc
) enables zwitterionic-controlled generation of peptide macrocyles from linear peptides and aldehydes. Containing a 1,3,4-oxadiazole, the resulting peptide exhibits both improved membrane permeability, lipophilicity, and aqueous solubility.
Different functional groups can be introduced by varying the aldehyde, and initial work used propionaldehyde (538124), phenylacetaldehyde (107395), and isovaleraldehyde (146455).
![]() |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
skychemical Co.Ltd
|
| Telephone: |
021-20960837,QQ1332204249 |
| Website: |
http://www.skychemical.com |
|