| Identification | Back Directory | [Name]
4-(Bromomethyl)phenylaceticacidphenacylester | [CAS]
7398-42-7 | [Synonyms]
Methyl 2-(4-(bromomethyl)
Methyl4-(bromomethyl)phenylacetate98%
Phenacyl=p-(bromomethyl)phenylacetate
Methyl 4-(bromomethyl)phenylacetate 98%
Methyl 2-(4-(broMoMethyl)phenyl)acetate
Bromomethylphenylaceticacidphenacylester
4-(BroMoMethyl)benzeneacetic acid Methyl ester
p-(Bromomethyl)phenylacetic acid phenacyl ester
4-(Bromomethyl)benzeneacetic acid phenacyl ester
Benzeneacetic acid, 4-(bromomethyl)-, methyl ester
2-Oxo-2-phenylethyl 2-(4-(broMoMethyl)phenyl)acetate
4-(2-Methoxy-2-oxoethyl)benzyl bromide, 4-(Bromomethyl)phenylacetic acid methyl ester
4-[(Methoxycarbonyl)methyl]benzyl bromide, 4-(Bromomethyl)phenylacetic acid methyl ester | [Molecular Formula]
C10H11BrO2 | [MDL Number]
MFCD07783030 | [MOL File]
7398-42-7.mol | [Molecular Weight]
243.1 |
| Chemical Properties | Back Directory | [Boiling point ]
290.6±20.0 °C(Predicted) | [density ]
1.415±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
White wooly crystalline solid | [Appearance]
White to yellow Solid | [InChI]
InChI=1S/C10H11BrO2/c1-13-10(12)6-8-2-4-9(7-11)5-3-8/h2-5H,6-7H2,1H3 | [InChIKey]
APXOMRFLJBRHNX-UHFFFAOYSA-N | [SMILES]
C1(CC(OC)=O)=CC=C(CBr)C=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
4-(Bromomethyl)phenylacetic acid phenacyl ester has reactive groups that allow it to be conjugated to amino acids or peptides with free amine or carboxylic acid groups.
| [Uses]
4-(Bromomethyl)phenylaceticacidphenacylester is used in the laboratory for the detection of protein-protein interactions. It can be conjugated to a protein target, such as human serum albumin, and then used as a hydrogen bond donor in an assay.
| [Synthesis]
4-(Bromomethyl)phenylaceticacidphenacylester is synthesized by reacting 4-(bromomethyl)phenylacetic acid with phenacyl bromide and potassium carbonate in chloroform.
| [References]
[1] Patent: WO2014/66659, 2014, A1. Location in patent: Paragraph 0616
[2] Patent: EP1939199, 2008, A1. Location in patent: Page/Page column 96-97
[3] Journal of Medicinal Chemistry, 2009, vol. 52, # 4, p. 1180 - 1189
[4] Patent: WO2015/137750, 2015, A1. Location in patent: Paragraph 710; 711
[5] Patent: WO2013/171281, 2013, A1. Location in patent: Page/Page column 169 |
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SynAsst Chemical.
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Cool Pharm, Ltd
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