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741656-40-6

741656-40-6 Structure

741656-40-6 Structure
IdentificationBack Directory
[Name]

L-HISTIDINE-13C6,15N3
[CAS]

741656-40-6
[Synonyms]

L-HISTIDINE-13C6,15N3
L-HISTIDINE-UL-13C,15N
[Molecular Formula]

C6H9N3O2
[MDL Number]

MFCD04118220
[MOL File]

741656-40-6.mol
[Molecular Weight]

164.24
Chemical PropertiesBack Directory
[Melting point ]

282 °C(lit.)
Hazard InformationBack Directory
[Uses]

L-Histidine-13C6,15N3 is 13C and 15N-labeled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9(11):e112141. DOI:10.1371/journal.pone.0112141
[3] Rama Rao KV, et al. Brain edema in acute liver failure: inhibition by L-histidine. Am J Pathol. 2010 Mar;176(3):1400-8. DOI:10.2353/ajpath.2010.090756
[4] Yoshikawa T, et al. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr. 2014 Oct;144(10):1637-41. DOI:10.3945/jn.114.196105
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