| Identification | Back Directory | [Name]
METHYL-D3-AMINE HYDROCHLORIDE | [CAS]
7436-22-8 | [Synonyms]
EOS-61951
Methyl-D3-amineCl
METHYL-D3-AMINE HCL
METHYL-D3-AMMONIUM CHLORIDE
METHYLAMINE-D3 HYDROCHLORIDE
(2H3)methylammonium chloride
Methan-d3-amine hydrochloride
METHYL-D3-AMINE HYDROCHLORIDE
Deuterated methylamine hydrochloride
Methyl-d3-amine hydrochloride,98+ atom % D
METHYL-D3-AMINE HYDROCHLORIDE, 99 ATOM % D
Methyl-d3-amine hydrochloride,Methyl-d3-ammonium chloride | [EINECS(EC#)]
231-089-6 | [Molecular Formula]
CH3ClD3N | [MDL Number]
MFCD00064559 | [MOL File]
7436-22-8.mol | [Molecular Weight]
70.54 |
| Chemical Properties | Back Directory | [Appearance]
white crystalline powder | [Melting point ]
232-234 °C(lit.)
| [solubility ]
DMSO, Methanol, Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Major Application]
pharmaceutical | [InChI]
InChI=1S/CH5N.ClH/c1-2;/h2H2,1H3;1H/i1D3; | [InChIKey]
NQMRYBIKMRVZLB-NIIDSAIPSA-N | [SMILES]
C([2H])([2H])([2H])N.Cl | [CAS DataBase Reference]
7436-22-8 | [CAS Number Unlabeled]
593-51-1 |
| Questions And Answer | Back Directory | [Preparation]
(i) reacting nitromethane with deuterium water under the presence of a base and a phase transfer catalyst to give deuterated nitromethane; and reducing the deuterated nitromethane in an inert solvent to form deuterated methylamine; then optionally reacting the deuterated methylamine with an acid to form METHYL-D3-AMINE HYDROCHLORIDE; or (ii) reacting N-(1,1,1-trideuterated methyl)benzosuccinimide with an acid to form METHYL-D3-AMINE HYDROCHLORIDE. |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline powder | [Uses]
Labelled Methylamine is useful in preparation of deuterated diphenylurea derivatives as phosphokinase inhibitors. | [Application]
Methyl-d3-amine hydrochloride can be used as a heavy isotope labeling reagent, paired with the light isotope reagent methylamine hydrochloride, to achieve relative quantitative analysis of intact N-glycopeptides. | [References]
[1]Sun, Z., Ji, G., Wang, G., Wei, L., Zhang, Y., & Lu, H. (2021). One step carboxyl group isotopic labeling for quantitative analysis of intact N-glycopeptides by mass spectrometry. Chemical Communications, 57(34), 4154-4157. |
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China Langchem Inc. Gold
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021-58956006,021-58950017 15800617331 |
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www.isotopemall.com/ |
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Energy Chemical Gold
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400-0056266 |
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www.energy-chemical.com |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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T&W GROUP
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www.trustwe.com/ |
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