| Identification | Back Directory | [Name]
diglycyl-histidine | [CAS]
7451-76-5 | [Synonyms]
GGH
Nsc 334195
diglycyl-histidine
L-Histidine,glycylglycyl-
N-(N-Glycylglycyl)histidine
diglycyl-histidine USP/EP/BP
L-Histidine, N-(N-glycylglycyl)-
2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoicaci
2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoic acid | [Molecular Formula]
C10H15N5O4 | [MDL Number]
MFCD00079323 | [MOL File]
7451-76-5.mol | [Molecular Weight]
269.26 |
| Chemical Properties | Back Directory | [Melting point ]
>210 °C (decomp) | [Boiling point ]
813.8±65.0 °C(Predicted) | [density ]
1.440 | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
solid | [pka]
2.82±0.10(Predicted) | [color ]
white | [InChI]
1S/C10H15N5O4/c11-2-8(16)13-4-9(17)15-7(10(18)19)1-6-3-12-5-14-6/h3,5,7H,1-2,4,11H2,(H,12,14)(H,13,16)(H,15,17)(H,18,19) | [InChIKey]
PDAWDNVHMUKWJR-UHFFFAOYSA-N | [SMILES]
[nH]1cnc(c1)CC(NC(=O)CNC(=O)CN)C(=O)O |
| Hazard Information | Back Directory | [Uses]
Gly-Gly-His has been used:
- as a peptide test probe in the hydrophilic interaction liquid chromatography (HILIC) studies
- in the electrochemical modification of back-side contact transducers (BSC) electrodes in copper (Cu2+) sensing studies
- for the fabrication carbon nanotube electrode for detection of Cu2+ ions
| [Definition]
ChEBI: Gly-Gly-His is an oligopeptide. | [Biological Activity]
Gly-Gly-His (GGH) tripeptide displays the affinity of copper (Cu2+) complexation. These complexes display good skin tolerance and may be useful in wound healing. GGH copper complexes are proposed to reduce tumor necrosis factor α (TNF-α)-based interleukin 6 (IL-6) secretion by in vivo studies with fibroblasts. GGH is used in comparative studies with other imidazole-containing peptides such as carnosine. An area of active application research involves the GGH binding of copper ions. |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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