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7461-02-1

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7461-02-1 Structure

7461-02-1 Structure
IdentificationBack Directory
[Name]

STYLOPINE, (-)-(RG)(CALL)
[CAS]

7461-02-1
[Synonyms]

Nsc404529
Coptisine, tetrahydro-
STYLOPINE, (-)-(RG)(CALL)
[Molecular Formula]

C19H17NO4
[MDL Number]

MFCD00075990
[MOL File]

7461-02-1.mol
[Molecular Weight]

323.343
Chemical PropertiesBack Directory
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Cryst.
Hazard InformationBack Directory
[Description]

Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.
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