| Identification | Back Directory | [Name]
Murabutide | [CAS]
74817-61-1 | [Synonyms]
Murabutide
N-acetylmuramyl-alanylglutamine-n-butyl ester
D-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-, butyl ester | [Molecular Formula]
C23H40N4O11 | [MDL Number]
MFCD00867587 | [MOL File]
74817-61-1.mol | [Molecular Weight]
548.58 |
| Hazard Information | Back Directory | [Uses]
Murabutide is a safe synthetic immunomodulator. Murabutide can reduce CD4 and CCR5 receptor expression and secrete high levels of beta-chemokines. Murabutide enhances nonspecific resistance against viral infections. Murabutide did not affect virus entry, reverse transcriptase activity or early proviral DNA formation in the cytoplasm of infected cells[1]. | [References]
[1] E C Darcissac, et al. The synthetic immunomodulator murabutide controls human immunodeficiency virus type 1 replication at multiple levels in macrophages and dendritic cells. J Virol. 2000, 74, 17. DOI:10.1128/jvi.74.17.7794-7802.2000 |
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