ChemicalBook--->CAS DataBase List--->74925-81-8

74925-81-8

74925-81-8 Structure

74925-81-8 Structure
IdentificationBack Directory
[Name]

3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine
[CAS]

74925-81-8
[Synonyms]

3-O-ACETYL-N2-ISOBUTYRYL-2-DG
3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine
3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine
Guanosine, 2'-deoxy-N-(2-methyl-1-oxopropyl)-, 3'-acetate
[Molecular Formula]

C16H21N5O6
[MDL Number]

MFCD00057881
[MOL File]

74925-81-8.mol
[Molecular Weight]

379.37
Hazard InformationBack Directory
[Uses]

3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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