| Identification | Back Directory | [Name]
NSC 136563 | [CAS]
75059-23-3 | [Synonyms]
NSC 136563
8-Allylthioadenosine
8-(2-Propenylthio)adenosine
Adenosine, 8-(2-propenylthio)- (9CI) | [Molecular Formula]
C13H17N5O4S | [MDL Number]
MFCD31814021 | [MOL File]
75059-23-3.mol | [Molecular Weight]
339.37 |
| Hazard Information | Back Directory | [Uses]
8-Allylthioadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020 |
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