ChemicalBook--->CAS DataBase List--->75220-84-7

75220-84-7

75220-84-7 Structure

75220-84-7 Structure
IdentificationBack Directory
[Name]

1H-1,5-Benzodiazepine, 4-(4-chlorophenyl)-2,3-dihydro-2-phenyl-
[CAS]

75220-84-7
[Synonyms]

Anticonvulsant agent 2
1H-1,5-Benzodiazepine, 4-(4-chlorophenyl)-2,3-dihydro-2-phenyl-
[Molecular Formula]

C21H17ClN2
[MOL File]

75220-84-7.mol
[Molecular Weight]

332.83
Chemical PropertiesBack Directory
[Melting point ]

129-130 °C
[Boiling point ]

492.2±45.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

6.10±0.60(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Anticonvulsant agent 2 is a potent and orally active anticonvulsant agent. Anticonvulsant agent 2 shows antiepileptic activity[1].
[in vivo]

Anticonvulsant agent 2 (compound10 a; 50 mg/kg, p.o.) decreases locomotor activity with an inhibition rate of 21.01% in rat[1].
Anticonvulsant agent 2 (50 mg/kg; p.o.) shows antiepileptic activity with an inhibition rate of 24.45% in rat[1].

Animal Model:180-250g, male Wistar rats[1]
Dosage:50 mg/kg
Administration:P.o.
Result:Showed antiepileptic activity with the inhibition rate of 24.45%.
[References]

[1] Verma R, et al. Design, synthesis and neuropharmacological evaluation of new 2,4-disubstituted-1,5-benzodiazepines as CNS active agents. Bioorg Chem. 2020 Aug;101:104010. DOI:10.1016/j.bioorg.2020.104010
75220-84-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Company Name: Proteintech China  
Tel: 027-87531629
Website: http://www.ptgcn.com
Tags:75220-84-7 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.