ChemicalBook--->CAS DataBase List--->75520-89-7

75520-89-7

75520-89-7 Structure

75520-89-7 Structure
IdentificationBack Directory
[Name]

(+)-Colchicine
[CAS]

75520-89-7
[Synonyms]

(R)-Colchicine
Colchicine (7R)-Isomer
(+)-(as,7R)-colchicine
Benzo[a]heptalene, acetamide deriv.
(R)-7-Acetylamino-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxybenzo[a]heptalene-9-one
(R)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetraMethoxy-9-oxobenzo[a]heptalen-7-yl)acetaMide
Acetamide, N-[(7R)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (R)-
(-)-N-[(R)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalene-7-yl]acetamide
[Molecular Formula]

C22H25NO6
[MDL Number]

MFCD01736983
[MOL File]

75520-89-7.mol
[Molecular Weight]

399.44
Chemical PropertiesBack Directory
[Melting point ]

106-132°C
[storage temp. ]

-20°C Freezer
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Uses]

The R-enantiomer of Colchicine (C640000). An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
[Definition]

ChEBI: (R)-colchicine is a colchicine that has (R)-configuration. It is an enantiomer of a (S)-colchicine.
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