| Identification | Back Directory | [Name]
Biotin-dPEG(R)3-benzophenone | [CAS]
756525-96-9 | [Synonyms]
Biotin-dPEG(R)3-benzophenone
N1-Biotinyl-N13-(4-Benzoylbenzoyl)-4,7,10-trioxa-1,13-tridecanediamine
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[1-(4-benzoylphenyl)-1-oxo-6,9,12-trioxa-2-azapentadec-15-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- | [Molecular Formula]
C34H46N4O7S | [MDL Number]
MFCD13184950 | [MOL File]
756525-96-9.mol | [Molecular Weight]
654.82 |
| Chemical Properties | Back Directory | [Boiling point ]
933.5±65.0 °C(Predicted) | [density ]
1.188±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
solid or viscous liquid | [pka]
13.90±0.40(Predicted) | [color ]
Off-white to light yellow | [SMILES]
O=C(NCCCOCCOCCOCCCNC(C1=CC=C(C=C1)C(C2=CC=CC=C2)=O)=O)CCCCC3C4NC(NC4CS3)=O |
| Hazard Information | Back Directory | [Uses]
Biotin-PEG3-benzophenone is biotin-labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite and a photosensitizer that has been implicated in photosensitive damage to DNA. Benzophenone causes nucleobase oxidation, formation of cyclobutane-pyrimidine dimers, single-strand breaks, DNA-protein cross-links or abasic sites, different pathologies that may occur in nucleosides, oligonucleotides or DNA [1]. | [reaction suitability]
reagent type: cross-linking reagent | [References]
[1] Cuquerella MC, Lhiaubet-Vallet V, Cadet J, Miranda MA. Benzophenone photosensitized DNA damage. Acc Chem Res. 2012 Sep 18;45(9):1558-70. DOI:10.1021/ar300054e |
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