ChemicalBook--->CAS DataBase List--->75783-45-8

75783-45-8

75783-45-8 Structure

75783-45-8 Structure
IdentificationBack Directory
[Name]

5-O-(tert-Butyldiphenylsilyl)-1,2-O-isopropylidene-alpha-D-erythro-pentofuranos-3-ulose
[CAS]

75783-45-8
[Synonyms]

1,2-O-Isopropylidene-3-oxo-5-TBDPS-alpha-D-xylofuranose
5-O-(tert-Butyldiphenylsilyl)-1,2-O-isopropylidene-alpha-D-erythro-pentofuranos-3-ulose
5-O-(t-Butyldiphenylsilyl)-1,2-di-O-isopropylidene-alpha-D-erythro-pentofuranos-3-ulose
5-O-(tert-Butyldiphenylsilyl)-1,2-di-O-isopropylidene-alpha-D-erythro-pentofuranos-3-ulose
5-O-[(1,1-Dimethylethyl)diphenylsilyl]-1,2-O-(1-methylethylidene)-α-D-erythro-pentofuranos-3-ulose
α-D-erythro-Pentofuranos-3-ulose, 5-O-[(1,1-dimethylethyl)diphenylsilyl]-1,2-O-(1-methylethylidene)-
(3aR,5R,6aS)-5-(((tert-Butyldiphenylsilyl)oxy)methyl)-2,2-dimethyldihydrofuro[2,3-d][1,3]dioxol-6(3aH)-one
(3aR,5R,6aS)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one
[Molecular Formula]

C24H30O5Si
[MDL Number]

MFCD22666288
[MOL File]

75783-45-8.mol
[Molecular Weight]

426.58
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,Room Temperature
Hazard InformationBack Directory
[Uses]

5-O-TBDPS-1,2-di-O-isopropy lidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
Spectrum DetailBack Directory
[Spectrum Detail]

5-O-(tert-Butyldiphenylsilyl)-1,2-O-isopropylidene-alpha-D-erythro-pentofuranos-3-ulose(75783-45-8)1HNMR
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