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758683-21-5

758683-21-5 Structure

758683-21-5 Structure
IdentificationBack Directory
[Name]

Bay 65-1942 (R forM)
[CAS]

758683-21-5
[Synonyms]

Bay 65-1942 (R forM)
Bay 65-1942 R-isomer
BAY 65-1942;BAY 65 1942
Bay 65-1942 R form (Bay 65-1942
7-[2-(Cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3R)-3-piperidinyl-2H-pyrido[2,3-d][1,3]oxazin-2-one
2H-Pyrido[2,3-d][1,3]oxazin-2-one, 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-1,4-dihydro-5-(3R)-3-piperidinyl-
[Molecular Formula]

C22H25N3O4
[MDL Number]

MFCD22666587
[MOL File]

758683-21-5.mol
[Molecular Weight]

395.45
Chemical PropertiesBack Directory
[Boiling point ]

521.8±50.0 °C(Predicted)
[density ]

1.286±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

8.07±0.35(Predicted)
[color ]

White to gray
Hazard InformationBack Directory
[Description]

Bay 65-1942 R form is an ATP-competitive and selective inhibitor of IKKβ kinase with IC50 value of 2 nM.
[target]

IKKβ
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