Identification | Back Directory | [Name]
2-Chloro-6-Methoxypurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside | [CAS]
758705-70-3 | [Synonyms]
2-Chloro-6-methoxypurine-9-β-D-(2’-deoxy-2’-fluoro)arabinoriboside 2-Chloro-6-Methoxy-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine 2-Chloro-6-Methoxypurine -9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-6-methoxy-9H-purine 2-CHLORO-6-METHOXY-9-(2-DEOXY-2-FLUORO-BETA-D-ARABINOFURANOSYL)-9H-PURINE | [Molecular Formula]
C11H12ClFN4O4 | [MDL Number]
MFCD25542515 | [MOL File]
758705-70-3.mol | [Molecular Weight]
318.689 |
Hazard Information | Back Directory | [Uses]
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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